Graceful aging isn’t about chasing perfection—it’s about preserving the radiant energy that already lives in your face. You know the look: smooth, rested, subtly lifted. Like you just took a nap in the sun and drank eight glasses of water, every single day.
That’s the quiet power of neurotoxins—they don’t freeze your face; they free it.
From smoothing crow’s feet and frown lines to contouring the jawline or softening neck bands, Botulinum toxin-based wrinkle relaxers are the gold standard for non-surgical facial rejuvenation. But there’s more than just Botox® on the scene—and knowing the difference can help you customize your perfect glow-up.
Let’s explore the different types of neurotoxins available today, how they work, and what makes each one unique.
What Are Neurotoxins? Let’s Break It Down
Neurotoxins, often referred to as facial muscle relaxants, are injectable treatments derived from Botulinum toxin type A. When injected into targeted facial muscles, these compounds temporarily block the nerve signals that cause muscle contractions.
The result? The overlying skin relaxes, smoothing out dynamic lines like:
- Forehead creases
- Crow’s feet
- Glabellar lines (aka frown lines)
- Lip lines
- Chin dimples
- Vertical neck bands
Unlike fillers, which add volume, neurotoxins focus on minimizing movement—especially in areas where repeated facial expressions cause creases to form. And here’s the elegant truth: with the right touch, neurotoxins don’t rob your face of emotion.
They restore balance—allowing your expressions to stay soft, lifted, and effortlessly youthful.
The Glow Guide: Your Neurotoxin Options Explained
What used to be a one-size-fits-all approach is now a beautifully tailored experience. With the evolution of injectables, patients can now choose from a range of options designed to suit their unique skin needs, treatment goals, and even personal preferences like onset time, longevity, and formulation purity.
Here’s a more in-depth look at the top neurotoxin treatments available—and how each one shines in its own way:
1. Botox®: The Classic That Keeps Evolving
Let’s start with the original icon. Botox® has long been the gold standard in wrinkle relaxers—and for good reason. It’s one of the most studied cosmetic treatments in the world, known for delivering reliable, precise, and refined results.
Botox® is ideal for treating:
- Frown lines (the “11s” between the brows)
- Forehead creases
- Crow’s feet
- Bunny lines on the nose
- Chin dimpling
- Vertical neck bands
Results usually begin to appear within 3 to 5 days, reaching full effect at around 2 weeks. The results last about 3 to 4 months, depending on your metabolism and treatment area.
Why patients love it: Botox® is tried, tested, and incredibly versatile. It works well for both first-timers and seasoned patients, delivering a polished, expressive look that’s easy to maintain.
Plus, it’s FDA-approved for therapeutic uses like Botox® for migraines and Botox® for excessive sweating, making it one of the most multi-functional neurotoxins available.
2. Dysport®: For Fast-Acting, Natural Smoothing
Next up is Dysport®, an FDA-approved injectable used to treat moderate to severe frown lines between the eyebrows. Known for its quick onset and ability to spread evenly, Dysport® is especially effective in larger treatment areas like the forehead thanks to its unique molecular makeup.
Results often appear in just 2 to 3 days—sooner than many other neurotoxins. While typical longevity ranges from 3 to 4 months, clinical studies have shown that some patients experience results lasting up to 5 months.
Why patients love it: Dysport® delivers smoother results, faster. It’s ideal for those with stronger facial muscles or more prominent expression lines, and the outcome is soft, subtle, and natural—never stiff or frozen.
3. Daxxify®: The Long-Wear Neurotoxin for Stubborn Frown Lines
If you want to stretch the time between appointments, Daxxify® is your new beauty ally. As the newest FDA-approved botulinum toxin on the market, Daxxify® offers something groundbreaking: up to 6 months of wrinkle relaxation, nearly double the duration of traditional neurotoxins.
Daxxify® uses a novel peptide-based stabilizer instead of human or animal-based proteins, making it a great choice for patients seeking a vegan-friendly option or those concerned about protein-related sensitivities.
Why patients love it: Daxxify® is the go-to for patients who love neurotoxins but don’t want the maintenance of quarterly visits. It’s a great fit for busy lifestyles or anyone looking to make fewer appointments without compromising results.
4. Xeomin®: The Clean Beauty of Neurotoxins
Xeomin® is often called the “naked” neurotoxin, and not just because it sounds trendy. What sets Xeomin® apart is its purified formula—it contains only the active botulinum toxin, without any accessory or complexing proteins.
This makes Xeomin® ideal for patients concerned about developing resistance to neurotoxins over time, as the simplified formulation may reduce the risk of the body forming antibodies that blunt the effect.
Results are typically seen in 3 to 4 days and last around 3 months.
Why patients love it: Xeomin® appeals to ingredient-conscious patients who want a cleaner formulation without sacrificing results. It’s especially great for long-term users who’ve noticed that other neurotoxins aren’t working quite as well anymore.
Beyond Wrinkle Relaxers: Hyperdilute Radiesse® for Enhnced Skin Quality
Let’s be clear: Hyperdilute Radiesse® isn’t technically a neurotoxin. It doesn’t relax muscles—it stimulates your body’s own collagen production. But it’s often used alongside neurotoxin treatments to improve overall skin quality in ways Botox® or Dysport® can’t touch.
When Radiesse (a calcium-based filler) is diluted with a combination of saline and lidocaine, it becomes thin enough to be injected across broader areas like the neck, chest, arms, or buttocks. It improves skin tone, texture, and elasticity, making it a dream for crepey or thinning skin.
Why patients love it: This treatment is perfect for patients who want to enhance firmness and glow—not just freeze lines. It helps the skin regenerate naturally over time, leading to a more lifted, radiant look that feels authentically youthful.
Choosing the Right Neurotoxin: It’s All About Your Story
Each neurotoxin has its own sweet spot. The right one for you depends on:
- Your treatment area (some diffuse better in broad zones like the forehead, while others are ideal for targeted spots like the brow or crow’s feet)
- Your lifestyle (if you travel a lot or prefer fewer touch-ups, longer-lasting options like Daxxify® may be ideal)
- Your goals (do you want maximum smoothing, minimal movement, or a mix of both?)
- Your skin history (if you’ve used neurotoxins before and seen reduced effectiveness, something like Xeomin® may work better)
The good news? You’re not expected to know all the answers on your own. That’s where expert guidance at Luminescence Aesthetics MedSpa comes in. Every patient journey starts with an in-depth consultation to assess your goals, skin dynamics, and muscle activity—because wrinkle care should be personal, never generic.
Who Are Neurotoxins Right For?
If any of these sound like you, neurotoxins might be your next favorite self-care ritual:
- You’re noticing wrinkles from repeated expressions (laughing, squinting, frowning)
- You want to delay the formation of fine lines before they settle in
- You’re looking for a non-invasive, fast treatment with visible results
- You love the idea of subtle refinement without losing your natural look
- You struggle with TMJ, migraines, or excessive sweating and want medical relief with aesthetic perks
Your Skin’s Best Era Starts Now
When your face feels more aligned with how you feel—rested, lifted, confident—that’s where real beauty lives. Neurotoxins don’t change you. They reconnect you to your glow.
At Luminescence Aesthetics MedSpa in Buffalo, NY, we believe aging is powerful—but that doesn’t mean you have to accept every line without options. With tools like Botox®, Dysport®, Xeomin®, Daxxify®, and Hyperdilute Radiesse®, you can shape your aesthetic journey with elegance, intention, and ease.
Let’s smooth the stress, soften the lines, and keep the spark. Because your next era should feel just as radiant as your last—maybe even more.
Call us today to schedule your consultation!
